Appetite Control: Hydroxycitric acid (HCA) is the most important active ingredient of Garcinia cambogia, which is attributed the properties in relation to the metabolism of fats. The two main benefits of HCA are:
1. Appetite Control: Reduction in the accumulation of fat in adipose tissue: inhibiting the formation of the enzyme ATP-citrate lyase, and therefore inhibiting lipogenesis from excess glucose. In addition there is a lower accumulation of fatty acids in adipose tissue.
2. Satiating properties: Increasing the release of serotonin in the brain, which is considerer as the main mechanism for appetite suppression. It also decreases serum leptin levels.
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They discover center of appetite control in the brain
In a study carried out with mice, scientists from the California Institute of Technology (Caltech) in the United States discovered a “central switch” in a group of neurons by means of which the desire to eat can be reduced. If it is demonstrated that this appetite control center also exists in humans, it could lead to new therapies against obesity or various eating disorders such as anorexia.
The research published in the journal Nature Neurosciences indicates that by stimulating the neurons by means of a laser beam, the rodents immediately stopped consuming food. In this case, nerve cells acted as a control center that combines and transmits messages to suppress appetite.
After activating the neurons of the mice and using chemicals to cause satiety, malaise, nausea and bitter taste on the palate. The researchers noted that the neurons remained active, suggesting that they could respond comprehensively to various stimuli.
The neurons studied are located in the cerebral amygdala, an almond-shaped center located in the temporal lobes. Whose function is the processing and storage of emotional reactions.
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In the study, this appetite control center reacted quickly when mice ingested a full meal. Indicating that they could also prevent overeating. “These cells make up the first well-defined center of the brain that manages to suppress appetite,” .
The next step of the study is to investigate how this group of neurons interacts with other nervous centers. Involved in the promotion of food consumption and to identify if there is a link between food and emotions.